The design of a fermenter involves the selection of materials; geometry; agitation system and control of variables; such as temperature; ph and oxygen; to optimize the fermentation of microorganisms or cells. in addition; aspects such as tank capacity; efficiency in heat and mass transfer; ease of cleaning and the integration of sensors to monitor the process in real time must be considered. an adequate design maximizes product yield; minimizes the risk of contamination and ensures reproducible conditions in each fermentation batch.